Preoperative anxiety is a major problem for surgical patients. A recent double-blind, placebo-controlled study investigated the use of a combination of melatonin and alprazolam as premedication to reduce anxiety more effectively than either drug alone. This article analyzes the study and its implications for clinical practice.
Treatment group | Key finding |
Alprazolam + Melatonin | Improved anxiety reduction without increasing sedation |
Just alprazolam | Effective in reducing anxiety, but not as much as a combination of |
Just melatonin | Some reduction in anxiety, but less than in alprazolam groups |
Placebo | No clinically significant reduction in anxiety |
Further studies may confirm the results in larger and more diverse patient samples. There is also potential to explore this combination for the treatment of anxiety in contexts other than preoperative care.
With evidence demonstrating enhanced anxiety reduction through the combination of melatonin and alprazolam prior to surgery, Bestia Melatonin capsules offer an ideal delivery format for harnessing the therapeutic benefits of melatonin.
Bestia Melatonin uses advanced liposomal encapsulation technology to optimize absorption and bioavailability. This innovative delivery system efficiently delivers the highest dose of melatonin to nerve cells.
Bestia Melatonin Capsules promote a healthy sleep cycle, antioxidant action, immune function and stress adaptation – perfectly complementing an anxiolytic premedication protocol. Their potent yet gentle properties make Bestia Melatonin capsules a recommended choice for combating pre-operative anxiety.
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An advertisement for a dietary supplement. There are reservations about use. Consult your physician before use. DMUA.BES.21.09.01.
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